PersistIQ vs Reply.io: Sales Engagement Platform vs Cold Email Platform Comparison
Compare PersistIQ (sales engagement platform) and Reply.io (cold email platform) side by side. See pricing, features, and integrations to decide which one, or both, your stack needs.
PersistIQ is a sales engagement platform built for multi-channel outreach and prospecting, priced by custom quote only. Reply.io is a cold email platform starting at $59/mo with a 1 billion B2B contacts database and unlimited email warmup. Teams needing email, phone, and social coordination lean PersistIQ; teams focused on high-volume cold email lean Reply.io.
Key takeaways
- Reply.io publishes an entry price of $59/mo, while PersistIQ uses custom, contact-sales pricing across all its plans.
- Reply.io offers four pricing tiers, ranging from $59/mo to $800/mo, compared to PersistIQ's single contact-sales tier.
- Reply.io lists a 1 billion B2B contacts database and unlimited email warmup as key features, neither of which appears on PersistIQ's feature list.
- PersistIQ integrates with 7 tools including Salesforce, Copper, Pipedrive, HubSpot, Gmail, Outlook, and Zapier, while Reply.io integrates with 9 tools including Zendesk Sell, Close, Make, and n8n.
- Both PersistIQ and Reply.io offer a 14-day free trial.
Reviewed and updated September 2, 2026
PersistIQ vs Reply.io: Sales Engagement Platform vs Cold Email Platform Comparison
PersistIQ is a sales engagement platform; Reply.io is a cold email platform. Whether you need one, the other, or both depends on which part of the workflow you are buying for: multi-channel sales outreach and engagement tracking on one side, cold email outreach on the other. This guide lays out what each vendor publishes.
The Quick Answer
PersistIQ is a sales engagement platform for multi-channel sales outreach and engagement tracking; Reply.io is a cold email platform for cold email outreach. By each vendor's own wording, PersistIQ lists multi-channel sales outreach and prospecting, and Reply.io lists unlimited email warmup and 1 billion b2b contacts database.
Reply.io publishes an entry price of $59/mo; PersistIQ uses custom pricing, so the two cannot be compared on list price.
If your priority is coordinating outreach across email, phone, and social channels, PersistIQ is the one built for it; for sending campaigns that land in the inbox and generate replies, that is Reply.io. Many teams run one of each.
Understanding the Core Difference
PersistIQ is Sales engagement platform for small teams that builds prospect lists, automates personalized email, call and task sequences, and syncs activity with a CRM.
Reply.io is AI-powered sales engagement platform with 1B+ B2B contacts, multichannel sequences, and AI SDR capabilities.
Both platforms offer 14-day free trial. Where they diverge is in their approach to pricing tiers and advanced capabilities.
Pricing Comparison
All plans
Email Volume
PersistIQ Pricing (as of September 2026)
| Plan | Price |
|---|---|
| All plans | Contact Sales |
Source: PersistIQ Pricing
Reply.io Pricing (as of September 2026)
| Plan | Price | Contacts | Emails |
|---|---|---|---|
| Email Volume | $59/mo | 1,000 active contacts | Unlimited |
| Multichannel | $99/mo | Unlimited active contacts | Unlimited emails; 10 mailboxes |
| Agency Core | $210/mo | Unlimited clients & users | Unlimited mailboxes |
| AI SDR Starter | $800/mo | 1,000 active contacts | Unlimited mailboxes & warm-ups |
Source: Reply.io Pricing
Pricing Analysis
One or both platforms use custom or contact-based pricing for some tiers. Reach out to their sales teams for exact quotes based on your usage needs.
Reply.io offers 4 pricing tiers compared to PersistIQ's 1, giving you more granularity as you scale.
Features Breakdown
- Multi-channel Sales Outreach
- Prospecting
- Sales Email AI
- Chrome Extension
- A/B test
- Reporting
- and 1 more listed below
- 14-day free trial
- Unlimited email warmup
- 1 billion B2B contacts database
- Anti-spam & deliverability suite
- LinkedIn automation (add-on)
- SMS and calls (add-on)
- AI personalization
- and 2 more listed below
PersistIQ Key Features
- Multi-channel Sales Outreach
- Prospecting
- Sales Email AI
- Chrome Extension
- A/B test
- Reporting
- CRM Integrations
- 14-day free trial
Reply.io Key Features
- Unlimited email warmup
- 1 billion B2B contacts database
- Anti-spam & deliverability suite
- LinkedIn automation (add-on)
- SMS and calls (add-on)
- AI personalization
- AI SDR capabilities
- Multi-workspace for agencies
- 14-day free trial
Shared Capabilities
Both PersistIQ and Reply.io include:
- 14-day free trial
The two lists below are a diff of each vendor's own feature list by exact wording, so a capability both tools offer can appear on either side under a different name.
Listed only by PersistIQ
- Multi-channel Sales Outreach
- Prospecting
- Sales Email AI
- Chrome Extension
- A/B test
- Reporting
- CRM Integrations
Listed only by Reply.io
- Unlimited email warmup
- 1 billion B2B contacts database
- Anti-spam & deliverability suite
- LinkedIn automation (add-on)
- SMS and calls (add-on)
- AI personalization
- AI SDR capabilities
- Multi-workspace for agencies
Integration Ecosystem
PersistIQ Integrations
PersistIQ connects with: Salesforce, Copper, Pipedrive, HubSpot, Gmail, Outlook, Zapier.
Reply.io Integrations
Reply.io connects with: HubSpot, Salesforce, Pipedrive, Copper CRM, Zendesk Sell, Close, Zapier, Make, n8n.
Shared Integrations
Both tools integrate with: Salesforce, Pipedrive, HubSpot, Zapier.
Integrations listed only by PersistIQ: Copper, Gmail, Outlook.
Integrations listed only by Reply.io: Copper CRM, Zendesk Sell, Close, Make, n8n.
Use Case Recommendations
Best Fit for PersistIQ
- Enterprise buyers who prefer custom pricing and dedicated support
- SDR teams running multi-channel outreach sequences
- Sales managers tracking team engagement metrics
- Revenue teams coordinating email, phone, and social touches
Best Fit for Reply.io
- Teams that need a wide feature set (9 capabilities listed)
- Organizations with complex tech stacks needing broad integration support (9 integrations)
- Sales teams running high-volume outbound email campaigns
- Agencies managing multiple client outreach programs
Feature Comparison Summary
| Feature | PersistIQ | Reply.io |
|---|---|---|
| Starting Price | Contact Sales | $59/mo |
| Top Tier Price | Contact Sales | $800/mo |
| Total Features Listed | 8 | 9 |
| Integrations | 7 | 9 |
Getting Started Checklist
- Define your multi-channel sales outreach and engagement tracking and cold email outreach requirements and monthly budget
- Estimate your expected sequences and engagement actions and email sending volume to find the right tier
- List the integrations your team currently relies on
- Sign up for free trials or demos of both platforms
- Run a small test with each tool before making a commitment
- Evaluate the onboarding experience and support quality
Final Thoughts
PersistIQ serves the multi-channel sales outreach and engagement tracking side of an outbound stack and Reply.io the cold email outreach side. Reply.io publishes an entry price of $59/mo, while PersistIQ uses custom pricing for its plans, so compare on features and on the quote you receive. Your decision should weigh pricing against the specific features that matter most for your workflow.
Start with a trial of each to see which platform fits your team's daily process. The best tool is the one your team actually uses consistently.
Pricing and features verified as of September 2026. Visit PersistIQ and Reply.io for current information.
Frequently asked questions.
Frequently asked questions- What is the main difference between PersistIQ and Reply.io?
- PersistIQ is a sales engagement platform designed for multi-channel outreach across email, phone, and social, with engagement tracking synced to a CRM. Reply.io is a cold email platform built around a 1 billion B2B contacts database, unlimited email warmup, and AI SDR capabilities. The choice depends on whether the priority is multi-channel coordination or high-volume email sending.
- How much does PersistIQ cost compared to Reply.io?
- PersistIQ does not publish pricing; all its plans require contacting sales for a custom quote. Reply.io publishes four tiers starting at $59/mo for its Email Volume plan, rising to $99/mo for Multichannel, $210/mo for Agency Core, and $800/mo for AI SDR Starter. This makes the two impossible to compare on list price alone.
- Which tool has more integrations, PersistIQ or Reply.io?
- Reply.io lists 9 integrations, including Zendesk Sell, Close, Make, and n8n, compared to PersistIQ's 7. Both platforms share integrations with Salesforce, Pipedrive, HubSpot, and Zapier, so the overlap covers the most common CRMs, with Reply.io adding a broader set of workflow and automation tools.
- Is PersistIQ or Reply.io better for agencies managing multiple clients?
- Reply.io is positioned as the better fit for agencies, offering an Agency Core plan at $210/mo with unlimited clients and users plus multi-workspace support. PersistIQ's feature list does not include an agency-specific tier or multi-workspace capability, making it less suited to managing multiple client outreach programs.
- Do both PersistIQ and Reply.io offer a free trial?
- Yes, both PersistIQ and Reply.io offer a 14-day free trial. This is listed as a shared capability between the two platforms, giving buyers a chance to test either tool before committing to custom pricing on PersistIQ or one of Reply.io's paid tiers.
About the author.
Tim Carden is CMO / CTO at RevenueFlow, which builds and operates outbound revenue engines for B2B companies. Studied at McGill University.
Tim Carden · CMO / CTO
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