Tool Comparisons

    Amplemarket vs Twenty: Sales Engagement Platform vs CRM Platform Comparison

    Compare Amplemarket (sales engagement platform) and Twenty (CRM platform) side by side. See pricing, features, and integrations to decide which one, or both, your stack needs.

    September 4, 20265 min read
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    The short answer

    Compare Amplemarket (sales engagement platform) and Twenty (CRM platform) side by side. See pricing, features, and integrations to decide which one, or both, your stack needs.

    Reviewed and updated September 4, 2026

    Amplemarket vs Twenty: Sales Engagement Platform vs CRM Platform Comparison

    Sales teams building an outbound stack often weigh Amplemarket, a sales engagement platform for multi-channel sales outreach and engagement tracking, against Twenty, a CRM platform for customer relationship management and sales pipeline tracking. They cover different parts of the workflow, so this comparison covers what each one does, what each one costs, and where they overlap.

    The Quick Answer

    Amplemarket is a sales engagement platform for multi-channel sales outreach and engagement tracking; Twenty is a CRM platform for customer relationship management and sales pipeline tracking. By each vendor's own wording, Amplemarket lists multichannel sequences and duo copilot ai sales agent, and Twenty lists full customization and ai agents with custom skills.

    Twenty offers a lower entry point at $9/mo compared to Amplemarket at $600/mo.

    If your priority is coordinating outreach across email, phone, and social channels, Amplemarket is the one built for it; for organizing contacts, tracking deals, and forecasting revenue, that is Twenty. Many teams run one of each.

    Understanding the Core Difference

    Amplemarket is AI sales copilot and multichannel engagement platform that combines a B2B contact and company database, intent signals, sequences across email, phone and social, and mailbox deliverability tooling for outbound sales teams.

    Twenty is Twenty is an open source CRM with full customization, AI agents with custom skills, workflows and email and calendar sync, offered as a hosted product priced per user per month. An Enterprise tier is quoted per year.

    The two platforms take different approaches to solving the same core challenge.

    Pricing Comparison

    $600/moAmplemarket entry plan

    Startup

    $9/moTwenty entry plan

    Pro

    Entry pricing for Amplemarket and Twenty, as published on each vendor's own pricing page.

    Amplemarket Pricing (as of September 2026)

    PlanPriceContacts
    Startup$600/mo27,000 contacts
    GrowthContact Sales140,000 contacts
    EliteContact Sales400,000 contacts

    Source: Amplemarket Pricing

    Twenty Pricing (as of September 2026)

    PlanPrice
    Pro$9/mo
    Organization$19/mo
    EnterpriseContact Sales

    Source: Twenty Pricing

    Pricing Analysis

    Twenty offers the lower entry point ($9/mo vs $600/mo). Teams watching their budget will appreciate the savings, especially when starting out.

    Features Breakdown

    Amplemarket lists
    • Multichannel Sequences
    • Duo Copilot AI sales agent
    • Duo Copywriter for personalized first-touch emails
    • Duo Voice for AI voice messages at scale
    • Duo Inbox with automatic draft replies
    • Contact and company search over a B2B database
    • and 4 more listed below
    Twenty lists
    • Full customization
    • AI agents with custom skills
    • Workflows
    • Emails and calendar sync
    • Folder and label import
    • Email sharing
    • and 2 more listed below
    What Amplemarket and Twenty each list on their own pages. The split is by exact wording, so a capability both offer can appear on both sides under different names.

    Amplemarket Key Features

    • Multichannel Sequences
    • Duo Copilot AI sales agent
    • Duo Copywriter for personalized first-touch emails
    • Duo Voice for AI voice messages at scale
    • Duo Inbox with automatic draft replies
    • Contact and company search over a B2B database
    • AI Intent Signals
    • Job change alerts on tracked contacts
    • Outbound Dialer for verified phone numbers
    • Domain Health Center with deliverability booster and spam checker

    Twenty Key Features

    • Full customization
    • AI agents with custom skills
    • Workflows
    • Emails and calendar sync
    • Folder and label import
    • Email sharing
    • Two-factor authentication
    • User roles and field-level permissions

    The two lists below are a diff of each vendor's own feature list by exact wording, so a capability both tools offer can appear on either side under a different name.

    Listed only by Amplemarket

    • Multichannel Sequences
    • Duo Copilot AI sales agent
    • Duo Copywriter for personalized first-touch emails
    • Duo Voice for AI voice messages at scale
    • Duo Inbox with automatic draft replies
    • Contact and company search over a B2B database
    • AI Intent Signals
    • Job change alerts on tracked contacts
    • Outbound Dialer for verified phone numbers
    • Domain Health Center with deliverability booster and spam checker

    Listed only by Twenty

    • Full customization
    • AI agents with custom skills
    • Workflows
    • Emails and calendar sync
    • Folder and label import
    • Email sharing
    • Two-factor authentication
    • User roles and field-level permissions

    Integration Ecosystem

    Amplemarket Integrations

    Amplemarket connects with: Salesforce, HubSpot, Pipedrive, Gmail, Microsoft 365, Zapier, Clay, Okta, CloudTalk, Orum, Nooks, SendSpark.

    Twenty Integrations

    Twenty connects with: .

    Integrations listed only by Amplemarket: Salesforce, HubSpot, Pipedrive, Gmail, Microsoft 365, Zapier, Clay, Okta, CloudTalk, Orum, Nooks, SendSpark.

    Use Case Recommendations

    Best Fit for Amplemarket

    • Mid-market to enterprise teams with established multi-channel sales outreach and engagement tracking budgets
    • Teams that need a wide feature set (10 capabilities listed)
    • Organizations with complex tech stacks needing broad integration support (12 integrations)
    • Enterprise buyers who prefer custom pricing and dedicated support

    Best Fit for Twenty

    • Budget-conscious teams looking for an affordable CRM platform
    • Enterprise buyers who prefer custom pricing and dedicated support
    • Sales teams tracking deals from first touch to close
    • Managers who need pipeline visibility and forecasting

    Feature Comparison Summary

    FeatureAmplemarketTwenty
    Starting Price$600/mo$9/mo
    Top Tier PriceContact SalesContact Sales
    Total Features Listed108
    Integrations120

    Getting Started Checklist

    1. Define your multi-channel sales outreach and engagement tracking and customer relationship management and sales pipeline tracking requirements and monthly budget
    2. Estimate your expected sequences and engagement actions and contacts and deals to find the right tier
    3. List the integrations your team currently relies on
    4. Sign up for free trials or demos of both platforms
    5. Run a small test with each tool before making a commitment
    6. Evaluate the onboarding experience and support quality

    Final Thoughts

    Amplemarket serves the multi-channel sales outreach and engagement tracking side of an outbound stack and Twenty the customer relationship management and sales pipeline tracking side. Twenty offers a more accessible entry point at $9/mo, while Amplemarket starts at $600/mo. Your decision should weigh pricing against the specific features that matter most for your workflow.

    Start with a trial of each to see which platform fits your team's daily process. The best tool is the one your team actually uses consistently.

    Pricing and features verified as of September 2026. Visit Amplemarket and Twenty for current information.

    AmplemarketTwentySales Engagement PlatformCRM PlatformComparisonsales-engagementcrm
    Byline

    About the author.

    Tim Carden

    Tim Carden is CMO / CTO at RevenueFlow, which builds and operates outbound revenue engines for B2B companies. Studied at McGill University.

    Tim Carden · CMO / CTO

    Connect on LinkedIn →
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